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Modes of Oxygen Delivery

Blake Funke


System L/min % O2 Comments
Blow by (ex: Trach collar) 21-100%
Nasal cannula 1-8 25 – 45%
Large bore nasal cannula Up to 15 Up to 65% Can be identified by larger bore tubing (often green) and nose piece. Colloquially referred to as HFNC at VUMC, but true HFNC = optiflow
Venturi mask 4 to 15 24 – 50% Actual FiO2 is dependent on pt effort
Non-rebreather 10 to 15 65-95% Often used as a bridge to higher level of O2 therapy
HFNC: Optiflow, AirVo, Vapotherm Up to 60 30-100% Delivers 0.5-1 cm/H2O of PEEP per 10L of flow

** Use of all of the above modes of O2 requires a spontaneously breathing pt

Non-invasive positive pressure ventilation:

  • CPAP
    • Indications: obstructive sleep apnea, tracheomalacia
    • Settings: CPAP, FiO2
  • BiPAP
    • Indications: hypercapnic respiratory failure (RF), hypoxic RF, pulmonary edema, obstructive sleep apnea, obesity hypoventilation syndrome, RF 2/2 neuromuscular disease
    • Settings: IPAP, EPAP, FiO2, RR (sometimes)
Mode You set Not set Comments
Pressure support (PS) PEEP
PS above PEEP
FiO2
TV
RR
Inspiratory flow
Similar to Bipap. Frequently used for vent weaning / SBT. Requires spontaneously breathing pt
Volume Control (AC/VC) PEEP
RR
TV
Inspiratory flow
FiO2
Inspiratory pressure Mandates a minute ventilation; limits volutrauma (i.e. can guarantee low tidal volume ventilation) **Primary mode used in MICU (mode used in major ARDS trials)
SIMV (Synchronized Intermittent Mandatory Ventilation) PEEP
RR
TV
PS above PEEP
FiO2
Pt gets VC breath for set rate, but if tries to breath over this will get PS breath; VC and PS breaths are synchronized when able
Pressure Control (AC/PC) RR
Inspiratory Pressure
PEEP
Inspiratory Time (or I:E ratio)
FiO2
TV Minimizes barotrauma (i.e. sets a max inspiratory pressure) → does not guarantee a specific minute ventilation (must monitor PCO2 with blood gases) Does not have natural ventilator alarms for protection – need to increase low minute ventilation alarm threshold
PRVC (Pressure Regulated Volume Control) PEEP
RR
TV
Inspiratory flow
Pressure max
FiO2
Adaptive pressure control (NOT actually a volume control mode); tries to limit both barotrauma and volutrauma but if in conflict, minute ventilation will drop (i.e. need to monitor PCO2 with blood gases like any other PC mode)
Con: More the pt works, the less the ventilator does
APRV / Bilevel PEEP (PLow)
Pressure High
Time Low
Time High
FiO2
TV Long periods of inspiratory holds and very brief expirations (i.e. releases), for refractory hypoxemia. Often difficult to ventilate pts on this mode